32 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the Evaluation ... and Management ... of Sickle Cell Crises ... Clinical Manifestations ... Workup #Algorithm #Ddxof
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... life-threatening • Treatment ... of SLE • Evolution
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... constitutional symptoms • Treatment ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... Usual therapeutic management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... cerebritis #diagnosis #management ... #treatment
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... renal histological evaluation ... #treatment #management ... #rheumatology #nephrology
REBEL Review 99: Serotonin Syndrome via Yosuf Alam, MSIV

Presentation: Altered mentd status, Seizures, Myoclonus, Hypertension, Hyperthermia
Hyperthermia (most common cause ... Diagnosis: Clinical ... Cornerstone of treatment ... fluid hydration; evaluation ... SerotoninSyndrome #management
Aortic Dissection Pearls
Aortic dissection is caused by a tear in the tunica intima, the innermost layer
dissection is caused ... the wall of the aorta ... Evaluation: 1. ... deficit • Shock Treatment ... Dissection #diagnosis #management
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Approach (when evaluation ... heart failure, neurologic ... 109 mm Hg) with clinical ... Coarctation of aorta ... Neurologic disorders
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Treatment depends ... maintained fever CAUSES ... Phaeochromocytoma Neurologic ... Checklist #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Drugs, Unknown cause ... Treatment: • ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management