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diagnosis treatment lupus differential summary vasculitis druginduced erythematosus systemic thrombocytopenia workup algorithm ana antibodies antibody antineutrophil antinuclear causes classification comparison
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
in drug-induced SLE ... connective tissue disease ... + 60% • Eosinophilic ... antibodies #diagnosis #rheumatology ... #diseases
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Active
Eosinophilic Granulomatosis ... Polyangiitis (EGPA) - ANCA ... Vasculitis Management ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Workup: - ANA ... of SLE • Evolution ... : Chronic disease ... #Summary #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• EGPA: - Eosinophilia ... < 30 years - Aorta ... branches • GCA: - Aorta ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Usual therapeutic management ... of SLE • Evolution ... : Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Antinuclear (ANA ... • Specific for SLE ... Erythematosus #SLE ... Summary #diagnosis #rheumatology ... #management
Eosinophilic Gastroenteritis: Treatment Options Based on Severity of the Disease Mild: • Trial of PPI • Trial
Eosinophilic Gastroenteritis ... Severity of the Disease ... Concern for HES: • Hematology ... consult for evaluation ... Gastroenteritis #Treatment #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... < 30 years • Aorta ... Arteritis): • Aorta ... Polyangiitis): • Eosinophilia ... Differential #Diagnosis #Rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
PT, aPTT(liver disease ... function test, ANA ... (e.g., SLE), anti-phospholipid ... - Bone marrow evaluation ... Causes #Workup #hematology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... Retroperitoneum and aorta ... phase reactants, eosinophilia ... #diagnosis #management ... workup #treatment #rheumatology
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