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hematology algorithm causes morphology approach bloodcell calculation classification cobalamin decrease dm2 elevation false hba1c hgba1c increase index key laboratory management
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
deficiency anemia ... : Vitamin B12 or ... deficiency anemia ... #diagnosis #hematology ... #microscopy #atlas
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... Deficiency • ... B12/Folate Deficiency ... Disease • Marrow
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... • Microcytic - Iron-deficiency ... , Thalassemia, Iron-deficiency ... #key #diagnosis ... #differential #
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
turnover • Iron ... deficiency • ... End-stage renal disease ... Increase #Decrease #Diagnosis ... #DM2 #Differential
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential ... Diagnosis Framework ... inflammation) • Iron ... , B12 deficiency ... Non-megaloblastic: Liver disease
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... disorders • Celiac ... disease Tissue ... malignancy • Iron ... deficiency anemia
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
deficiencies: Iron ... loss), Vitamin B12 ... Chronic kidney disease ... #differential # ... diagnosis #calculation
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... related to IBD, celiac ... disease, other ... total body stores Evaluation ... • Labs: - CBC
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