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differential algorithm deficiency hematology gastroenterology nutrition classification cobalamin low management mcv aafp abdominal alkaline alp anosmia approach dysfunction euvolemic falls
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (<80 fL) • Iron ... of Chronic Disease ... of Chronic Disease ... (>100 fL) • B12
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Gastrointestinal Evaluation ... with anemia, diagnose ... inflammation or chronic ... tests Test for celiac ... disease with serology
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
Disease - Diagnosis ... • Signs and symptoms ... disease • Iron-deficiency ... anemia unresponsive ... #Disease #Diagnosis
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Drugs, H pylori, Celiac ... disease (↑ hepcidin ... #differential #diagnosis ... #anemia #nutrition
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Elite athletes • Chronic ... Loss (without anaemia ... Bleeding, Edema, Celiac ... #differential #diagnosis
Differential Diagnosis and Evaluation of Hyponatremia: 1) Identification of onset (acute vs. chronic) 2) Presence of symptoms (HA,
and Evaluation ... onset (acute vs. chronic ... 2) Presence of symptoms ... , liver, renal disease ... #EM #IM #Nephro
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Deficiency • B12 ... • Anemia of Chronic ... Disease • Marrow ... #Algorithm #Causes
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... disorders • Celiac ... disease Tissue ... malignancy • Iron ... deficiency anemia
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... Microcytic" • Iron ... disease, Acute ... Megaloblastic: Vitamin B12 ... #causes #hematology
Causes of Low Vitamin B12 Levels Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people Autoimmune
Causes of Low Vitamin ... B12 Levels Low ... vitamin B12 intake ... , coeliac disease ... #differential #diagnosis
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