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differential algorithm hematology iron nutrition thrombocytosis classification cobalamin gastroenterology management pediatrics abdominal alopecia approach b12 bleeding bruising cardiology ck creatine
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Increased Body Needs: Infants ... Elite athletes • Chronic ... Bleeding, Edema, Celiac ... #differential #diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Infectious: • Acute ... disorders • Celiac ... malignancy • Iron deficiency ... anemia #Thrombocytosis
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Gastrointestinal Evaluation ... with anemia, diagnose ... inflammation or chronic ... tests Test for celiac ... #Evaluation #workup
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... of chronic kidney ... disease, Acute ... #differential #diagnosis ... #causes #hematology
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Drugs, H pylori, Celiac ... Inflammation: IBD, Chronic ... #Causes #differential ... #diagnosis #anemia
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... - Differential Diagnosis ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute ... • Early Iron Deficiency
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Blood Loss • Acute ... RBCs on Smear • Chronic ... • Anemia of Chronic ... #Algorithm #Causes
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential Diagnosis ... Thrombocytosis): • Acute ... malignancies • Anemia ... specifically: iron deficiency
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... - Differential Diagnosis ... intake for needs: Infancy ... of absorption): Celiac ... #Causes #Fe #algorithm
Differential Diagnosis and Evaluation of Hyponatremia: 1) Identification of onset (acute vs. chronic) 2) Presence of symptoms (HA,
and Evaluation ... Identification of onset (acute ... vs. chronic) 2) ... symptoms (HA, nausea ... Differential #Algorithm #Ddxof
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