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diagnosis differential anemia algorithm hematology nutrition alopecia gastroenterology hairloss approach b12 bleeding bruising classification cobalamin copper diffuse fe ferritin focal
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Gastrointestinal ... Evaluation of Iron ... tests Test for celiac ... disease with serology ... #Gastrointestinal
Gastrointestinal Causes of Iron Deficiency Anemia • Mass lesions: Carcinoma, Large polyps • Inflammatory: Reflux esophagitis,
Gastrointestinal ... Causes of Iron ... Deficiency Anemia ... or colon ulcer, Celiac ... #Iron #Deficiency
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Chronic Blood Loss ... Bleeding, Edema, Celiac ... Disease (IBD, cancer ... ) #Iron #Deficiency
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency ... sTfR • Blood loss ... loss: Intravascular ... - Structural: Celiac ... disease, Tropical
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Drugs, H pylori, Celiac ... Athletes • Blood Loss ... : IBD, Chronic disease ... #Deficiency #Causes
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... Chronic kidney disease ... of absorption): Celiac ... disease, Bypass ... #Diagnosis #Causes
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
disorders • Celiac ... disease Tissue ... malignancy • Iron ... deficiency anemia ... #Hematology
Causes of Copper Deficiency - Differential Diagnosis Hereditary: - Menkes disease, familial hypoceruloplasminemia Decreased / Inadequate Intake:
Causes of Copper ... Deficiency - Differential ... Increased copper loss ... , Celiac sprue, ... supplementation) or iron
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Algorithm Blood Loss ... Deficiency • ... Anemia of Chronic Disease ... Diagnosis #Algorithm #Causes ... #Hematology
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Capitis - Skin Disease ... of any comorbid disease ... Scaling, pustules, crusts ... • Laboratory evaluation ... Differential #Diagnosis #dermatology
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