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differential algorithm management anemia bleeding gastroenterology iron rheumatology summary table thrombocytosis workup alopecia b12 bruising cardiology causes clinical coagulation cobalamin
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Malabsorption (e.g. celiac ... disease, CF, IBD ... Advanced Liver Disease ... Summary #table #comparison ... #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... disorders • Celiac ... disease Tissue ... malignancy • Iron deficiency ... #Differential #Diagnosis
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Gastrointestinal Evaluation ... patients with anemia, diagnose ... tests Test for celiac ... disease with serology ... #workup #diagnosis
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
- Differential Diagnosis ... - Structural: Celiac ... disease, Tropical ... #Differential #Diagnosis ... Algorithm #ferritin #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Acute hemolysis, deficiency ... Vasculitides, IBD, Celiac ... disease, Kawasaki ... #Differential #Diagnosis
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... administration, evaluation ... The appropriate evaluations ... #Differential #Diagnosis ... #Hematology
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
- Differential Diagnosis ... Capitis - Skin Disease ... of any comorbid disease ... • Laboratory evaluation ... #Differential #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Adult-onset Still disease ... Cellular immune deficiency ... inhibitors under evaluation ... treatment #summary #rheumatology
Celiac Disease - Diagnosis Algorithm IgA TTG has high sensitivity and specificity of ~ 98% and is
Celiac Disease - ... Diagnosis Algorithm ... serologic marker for evaluating ... IgA deficiency affects ... #Disease #Diagnosis
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... related to IBD, celiac ... disease, other ... total body stores Evaluation ... #diagnosis #management
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