1771 results
Abnormal Lipid Profiles - Differential Diagnosis Algorithm

Increased Cholesterol and Triglycerides 
 - Genetic Causes
• Tangier Disease ... • Familial Defective ... Obstructive Liver Disease
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Thrombasthenia • Defective ... Bernard-SouIier • Defective ... Von Willebrand Disease
Factor VIII synthesis - Normal, Haemophilia A and Von Willebrand Disease

Normal - vWF carrier protein protects
Von Willebrand Disease ... Haemophilia A - Defective ... Von Willebrand Disease ... VonWillebrand #Disease
Characteristics of Common Lipid Disorders
Polygenic hypercholesterolemia
Atherogenic dyslipidemia
 • Frequently accompanied by central obesity or diabetes
Familial hypercholesterolemia,
life Familial defective ... lipid #disorders #diseases
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
Hypophosphatasia -> Defective ... Pseudogout #CPPD #Disease
Types of Renal Calculi

Calcium oxalate
 - Interstitial apatite plaque, Low urine volume, Increased urinary calcium excretion,
- Cystinuria, Defective ... recessive genetic disease
lodine deficiency
Food
lodine excess
Stress
Catecholamines
Estrogens
Carrier defect
Nat
TRH
Hypothalamic lesion
Dopamine
Somatostatin
Glucocorticoids
TSH
Pituitary insufficiency
Autoimmune disease
TSI
Peroxidase
Peroxidase deficiency
ОН
TG
DIT
Coupling
ОН
Cell proliferation
Thyroglobulin
TG
Cell damage by tumor, inflammation, etc.
Proteolysis
Goiter
TG
MIT
ОН
Defective conversion
T4
TG
TG
Storage
Colloid
Genetic defect,
insufficiency Autoimmune disease ... TG MIT ОН Defective
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
congenital heart disease ... interstitial lung disease ... inflammatory bowel diseases ... Seen in liver disease ... plate caused by defective
Abiotrophia defectiva on Blood Culture and Microscopy
 - only growing on Chocolate Agar
 - Gram pos
Abiotrophia defectiva ... #Abiotrophia #defectiva
Paths to Defective Homologous Recombination DNA Repair in Breast Cancer. Each individual mutation or epigenetic aberration
Paths to Defective ... summed together, defective