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Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal

PRE-RENAL 
Impaired perfusion: 
•
of Acute Kidney Injury ... Blood loss • Dehydration ... Acute #Kidney #Injury
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... Classification Prerenal: • Dehydration ... Acute #Kidney #Injury
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
causing Acute Kidney Injury ... ) Prerenal: • Dehydration ... Acute #Kidney #Injury
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Prerenal:
 • Due to true volume loss or decreased
Acute Kidney Injury ... • Hypovolemia: Dehydration ... Acute #Kidney #Injury
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
in the heat - Dehydration ... sweat Heat Injury ... Extreme weakness - Dehydration ... damage (AKI, Liver injury ... Profuse sweating, Dehydration
Shock Classification and Differential Diagnosis
SHOCK
 • MAP <65, SBP <90, drop in SBP > 40
 •
Medications, Spinal Cord Injury ... Spacing, Extreme Dehydration
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Medications, Spinal Cord Injury ... Spacing, Extreme Dehydration
Radiation Injury
Acute Radiation Toxicity primarily affects rapidly dividing cells based on dosage
Hematopoiteic - Pancytopenia, Infection
 •
Radiation Injury ... days GI - N/V, Dehydration ... #Radiation #Injury
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
ongoing rhabo, crush injury ... agent (ACE-I. dehydration
Urine Specific Gravity - Interpretation
Specific Gravity = Density of urine / Density of water
SG close to
: • Excessive hydration ... close to 1.035: • Dehydration