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rheumatology autoantibodies differential associations diseases erythematosus lupus symptoms syndrome systemic table ana anca antibody antineutrophil antinuclear behcet classification disease hemeonc
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... antibodies) • ... Anti-cardiolipin (aCl ... Polymerase Ill • ANCA Vasculitis ... #diagnosis #associations
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
syndrome Anti-Scl ... disease c-ANCA - Vasculitis ... Associations #diseases #diagnosis ... #table #rheumatology ... #antibodies
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... in drug-induced SLE ... scleroderma) - Anti-Scl ... ANCA-Associated Vasculitis ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
involvement 3% SLE-Related ... Auto-Antibodies ... Lupusreference #SLE ... autoantibodies #signs ... #differential #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... purpura: strong sign ... C-ANCA) pattern: antibodies ... , and SLE) • Urinalysis ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... Differential Diagnosis ... -70, RNP antibodies ... anticardiolipin antibodies ... Erythematosus #Diagnosis
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
and Management ... Confirmatory test ↑Se ... D/c all heparin ... , Bivalirudin, DOAC ... #Hematology #HemeOnc
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... Oral aphthae : SLE ... • Arthritis: SLE ... #management #signs ... #symptoms #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ) • Cutaneous vasculitis ... Nephrogenic DI Hematologic ... : 2% Systemic Vasculitis ... #Diagnosis #Management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... Disorders: - SLE ... - Sjogren - Vasculitis ... Antiamphiphysin antibodies ... #management #neurology
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