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hematology algorithm causes anemia management oncology classification nutrition workup comparison erythematosus lupus mcv neurology sle systemic thrombocytosis arthritis atlas bleeding
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Approach to Anemia - Differential ... Diagnosis Framework ... -100): • Non-hemolytic ... Non-megaloblastic: Liver disease ... #Diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... Consider RBC membrane disorder ... #Anemia #Differential ... #workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... lymphoproliferative disorders ... G6PD deficiency) ... Extravascular #Causes #differential ... #diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
) - Differential ... Diagnosis Algorithm ... • Bleeding • Hemolysis ... #Diagnosis #Algorithm ... #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Approach to Anemia - Differential ... Diagnosis Algorithm ... Anemia of Chronic Disease ... #Diagnosis #Algorithm ... #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Microangiopathic Hemolytic ... Unstable hemoglobin disorders ... Cold autoimmune hemolytic ... RBC #Morphology #differential ... #diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Bleeding / Bruising - Differential ... Diagnosis Algorithm ... Sequestration Disordered ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... specifically: iron deficiency ... , hemolysis, hemorrhage ... Chronic inflammatory disorders ... myeloid leukemia (CML
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... Diagnosis: • hemolytic ... younger pts) Differential ... IgM Includes Disorders ... #hematology #diagnosis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Corpuscular Volume (MCV ... ) - Differential ... Diagnosis Algorithm ... • Early Iron Deficiency ... #Causes #Hematology
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