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sle treatment syndrome anesthesia checklist classification dermatology dermatomyositis druginduced erythematosus hemophagocytic hlh intraoperative lymphohistiocytosis summary symptoms systemic workup activation ana
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
suspected) • In case ... • Special cases ... Measurement #SLE #rheumatology ... pharmacology #levels #lupus ... #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... and Management ... Positive in 60-80% of cases ... Erythematosus #Diagnosis ... #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... permeability Diagnosis ... CNS #neurology #rheumatology ... #cerebritis #diagnosis ... #management #treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
cases, drug-dependent ... Discontinuation of causal ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Cardiac Tamponade - Guidelines for Crises in Anaesthesia Caused by an accumulation of blood, pus, effusion fluid
• Diagnostic ... examination and vital signs ... Plan definitive management ... Cardiac #Tamponade #Anesthesiology ... #Management #Workup
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... scleroderma) - Anti-Scl ... seen in 30—70% of cases ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Ferritin >1000 ng/ml ... sIL-2R >2400 Ul/ml ... Drugs, Unknown cause ... #management #treatment ... #summary #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
chest (in a V-sign ... dorsal part of the MCP ... Inverse Gottron’s sign ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia • Unexplained hypotension • Unexplained bronchospasm (wheeze may be absent
of more of the signs ... 4 ⓫ Take 5-10 ml ... #Anaphylaxis #Anesthesiology ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... Diagnosis via genetic ... Ferritin >500 ng/mL ... #management #treatment ... #hematology
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