40 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... : >3 symptoms, or ... #APML #diagnosis ... #management #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Management Summary Diagnostic ... transformation into AML ... • Treatment algorithms ... von Willebrand disease ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... extramedullary disease ... smear: Blasts APML ... #Leukemia #Hematology ... #Oncology #Diagnosis
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
- Differential Diagnosis ... Algorithm Normal ... • Prader-Willi ... • Cushing's Disease ... Panhypopituitarism Treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... lethargy, hematuria, cardiac ... with tetany or cardiac ... #TLS #diagnosis ... #management #hematology
Restrictive Cardiomyopathy - Diagnosis and Causes
Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema)
Physical
Cardiomyopathy - Diagnosis ... ↑ "Right Sided-Symptoms ... Echocardiography, Cardiac ... Hyper-eosinophilc Syndrome ... differential #cardiology #algorithm
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... thrombosis, VTE) • Cardiac ... Arthritis, AS Treatment ... #signs #symptoms ... #rheumatology #
ISCHEMIA Trial - Management Algorithm for patients with Stable Angina

Stress Test -> ? +moderate or severe
LMCA lesion -> Cardiac ... revascularization (PCI ... with a stable symptom ... acute coronary syndrome ... Angina #ChestPain #Diagnosis
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
- Differential Diagnosis ... pathogens, including PML ... Antimicrobial treatment ... Hydrocephalus possible PML ... Demyelinating disease