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management differential oncology rheumatology signs syndromes arthritis bariatric behcet bypass cancer causes chronic cll complications differentiation diuresis diuretics emergencies endocrinology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... : >3 symptoms, or ... Anaphylaxis, Acute Renal ... #APML #diagnosis ... #management #hematology
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
- Differential Diagnosis ... Algorithm Normal ... • Prader-Willi ... Panhypopituitarism Treatment ... Celiac, IBD) • Renal
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Management Summary Diagnostic ... transformation into AML ... • Treatment algorithms ... von Willebrand disease ... #hematology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... Inflammatory eye disease ... (UPC) ratio • Cardiac ... or serologies + symptoms ... #treatment
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... thrombosis, VTE) • Cardiac ... Arthritis, AS Treatment ... #signs #symptoms ... #rheumatology #
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Agents Regulating Renal ... • Diagnosis of ... Inhibitors of Na+K+2Cl ... • Bleeding • Cardiac ... Tolvaptan) • Treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... 5% of patients Cardiac ... APLA/LAC: • Renal ... Cytopenias • Cardiac ... Induced Lupus: • Symptoms
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... cells can indicate disease ... microglobulin Treatment ... Transform to DLBCL, PML ... workup #oncology #hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... left heart 3-6 cardiac ... ) on room air Treatment ... resolution of symptoms ... #treatment #hepatology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
): - Hematologic ... : - Seen with AML ... (~20 %) and APL ... , hypotension, renal ... Oncology #HemeOnc #Diagnosis
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