15 results
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Incidence, Symptoms ... , Complications ... and Treatment ... #Pharmacology # ... Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... thrombocytopenia Complications ... Constitutional symptoms ... Lymphocytic #Leukemia #oncology ... hematology #hemeonc #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... phenomenon CLL Diagnosis ... microglobulin Treatment ... Transform to DLBCL, PML ... #workup #oncology
UCSF COVID-19 Adult Clinical Evaluation Guide - Updated April 10 2020

Clinical Presentation
• Fever: hospitalized pts but
30%; can be only symptom ... 3-12% • Cardiac ... incr in 27-75% • PCT ... 28% -> Incr risk complications ... Evaluation #Guide #Diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... : >3 symptoms, or ... Renal Failure Treatment ... fluid overload, PCC ... management #hematology #oncology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
severe clinical complications ... thiamine) Late: • Cardiac ... overload) Other Symptoms ... hyperparathyroidism Treatment ... #Differential #Diagnosis
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Antibiotics (Bactrim, PCN ... tourniquet / IVF line draw ... line, stabilizes cardiac ... #Hyperkalemia #Diagnosis
Premature Ventricular Complexes (PVC's) - Summary Framework

Why PVCs?  Can be the first manifestation of cardiac
manifestation of cardiac ... Digoxin toxicity Symptoms ... Differential Diagnosis ... fibrillation Complications ... more intensive treatment
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome • Diagnosis ... Inhibitors of Na+K+2Cl ... • Bleeding • Cardiac ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
its Chloride (Cl ... are balanced by Cl ... Hyperkalemia, a complication ... criticalcare #management #diagnosis ... #treatment #pharmacology