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anemia algorithm bleeding hemolytic management rheumatology arterial atlas basics blood cryofibrinogenemia elevatedmcv embolism hemolysis hemostasis hodgkins intravascular key lesions lymphoma
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... thrombocytopenic purpura ... lymphoproliferative disorders ... #Causes #differential ... #diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... #Causes #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... deficiency • Liver ... Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... Congenital heart disease ... #Bruising #Causes ... #peds #pediatrics ... #diagnosis #differential
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... : • Liver disease ... #Diagnosis #causes ... #classification ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Diagnosis Algorithm ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Causes #Hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... Diagnosis Framework ... von Willebrand syndrome ... discern these causes ... #Diagnosis #Hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Myeloproliferative disease ... • Nephrotic Syndrome ... , Ischemic Liver ... of purpura fulminans ... pathophysiology #hematology
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... flat macules of extravascular ... a generalized disorder ... nettle sting #Diagnosis ... #Dermatology #Skin
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulinemia Associated Disorders ... Skin necrosis • Purpura ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... hematology
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