39 results
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... • Bleeding • Hemolysis ... Renal Disease, Liver ... #MCV #Classification ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... #differential # ... diagnosis #hematology ... #anemia
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
(e.g. methotrexate ... , Liver disease, ... Microangiopathic Hemolytic ... RBC #Morphology #differential ... #diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... : • Liver disease ... #Anemia #Differential ... #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
, Liver diseases ... , Liver diseases ... Morphology #Atlas #key #diagnosis ... #differential # ... hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
- Differential ... Diagnosis Algorithm ... Inflammatory • Systemic ... Serum Sickness Hemolytic ... #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... aciduria, Drugs (e.g ... Non-megaloblastic: Liver ... disease, Alcoholism ... #Diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Diagnosis Algorithm ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Causes #Hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... : • Systemic lupus ... Antibody-mediated hemolysis ... #Diagnosis #Hematology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Iron deficiency anemia ... discoloration) • Liver ... #Differential # ... Diagnosis #Algorithm ... #causes