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management oncology algorithm anemia bruising hodgkins lymphoma acquired cerebritis cns comparison cryofibrinogenemia cryoglobulinemia cryoglobulins erythematosus hemolysis hemolytic hemostasis intravascular lupus
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Causes Intravascular ... ) - HELLP syndrome ... #Causes #differential ... #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... . autoimmune, TB ... Myelodysplastic syndrome ... Diagnosis #Causes ... #hematology #secondary
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm ... Rare • Drugs (e.g ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... 80-100 fL) • Bleeding ... (e.g. ... #Anemia #MCV #Classification ... #Causes #Hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
- Diagnosis and ... thrombocythemia), Autoimmune ... disease • vWF ... #treatment #hematology ... #differential
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
diseases (e.g., ... translocation • Types: Classification ... Hepatosplenomegaly, cytopenias(bleeding ... #differential # ... hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... Diagnosis Neonate ... hypertension and/or drug treatment ... #diagnosis #causes ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... Lumbar Puncture, EEG ... #rheumatology #
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Paradoxical spontaneous bleeding ... associated with autoimmune ... Antiphospholipid syndrome ... #rheumatology # ... hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... diseases: - 10% ... #types #classification ... #rheumatology #
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