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algorithm anemia bruising rheumatology workup arterial ascites bleeding blood dermatology embolism extravascular hemolysis hemolytic hemorrhage management mcv mds myelodysplasia myelodysplastic
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... #Causes #differential ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... : - Thrombocytopenia ... #Differential # ... Diagnosis #hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... (disseminated intravascular ... Congenital heart disease ... #peds #pediatrics ... #diagnosis #differential
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... Diagnosis Algorithm ... • HELLP syndrome ... • Disseminated intravascular ... von Willebrand's disease
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Thrombocytopenia ... Rare • Drugs (e.g ... • Disseminated Intravascular ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Diagnosis Algorithm ... Disease (e.g. ... #Anemia #MCV #Classification ... #Causes #Hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Myeloproliferative disease ... • Nephrotic Syndrome ... - Disseminated intravascular ... of purpura fulminans ... pathophysiology #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Purpura Activity ... hallmark for the disease ... reflection of intravascular ... #Workup #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Diagnosis Framework ... Eosinophilia, asthma, chronic ... tract, and often causes ... #diagnosis #rheumatology ... #classification
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
most common causes ... more than one cause ... (e.g. cirrhosis ... of underlying disease ... #Diagnosis #hepatology
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