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algorithm anemia management thrombocytosis acidosis ascites blood dili druginduced elevatedmcv elevation exposure injury lactate lactic leukostasis liver lysis macrocytic macrocytosis
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Blood Loss • Acute ... Reticulocytes, MCV ... Anemia of Chronic Disease ... #Approach #Differential ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... ) - Differential ... (e.g. ... #Classification ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Infectious: • Acute ... disorders • Celiac disease ... Tissue Damage: ... effect following treatment ... #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
(Morphological Approach ... , Acute blood loss ... #differential # ... diagnosis #causes ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... → Refer to hematology ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - APLS • Acute ... Scurvy - Actinic damage ... #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Corpuscular Volume (MCV ... ) - Differential ... Myelodysplastic Syndromes ... #Causes #Hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... Alcohol-related liver disease ... dechallenge • Acute ... #Algorithm #hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - ACS, AKI, acute ... signs of end organ damage ... #TLS #diagnosis ... #management #hematology
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
Approach and Differential ... most common causes ... (e.g. cirrhosis ... of underlying disease ... #Diagnosis #hepatology
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