ecg qtc syndrome acltear hematology disease differential classification causes hepatology rheumatology anemia diagnosis pulmonary workup chronic morphology elevatedmcv

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Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80

Causes of Anemia ... of Chronic Disease ... of Chronic Disease ... #MCV #Classification ... #Causes #Hematology

Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
•

Causes of Anemia ... Diagnosis Algorithm ... Myelodysplastic Syndromes ... #Macrocytosis #elevatedMCV ... #Causes #Hematology

Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),

Blood Cell (RBC) Morphology ... , Chronic disease ... Chemotherapy (e.g ... #differential # ... diagnosis #hematology

Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or

Causes of Anemia ... Causes: Chronic ... HgbE, HgbC, etc. ... #Macrocytosis #elevatedMCV ... #Causes #Hematology

Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
• Iron deficiency

Myelodysplastic syndrome ... #morphologic #mcv ... #differential # ... diagnosis #causes ... #hematology

Red Blood Cell (RBC) Morphology Atlas
• Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning

Blood Cell (RBC) Morphology ... PD deficiency, Pulmonary ... #Atlas #key #diagnosis ... #differential # ... hematology

Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?

→ Refer to hematology ... for workup, including ... hemolysis, deficiency anemia ... • Infections: Chronic ... #hematology

Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
• Acute infection
• Solid organ

- Differential ... malignancies • Anemia ... Myelodysplastic syndrome ... #Diagnosis #Causes ... #hematology #secondary

Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
• Acute Bleed - Normocytic / Normochromic

- Differential ... • Anemia of Chronic ... Disease • Marrow ... #Classification ... #Causes #Hematology

Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
• Mechanical Trauma (Microangiopathic hemolytic anemia):

Diagnostic Framework ... Extravascular Causes ... #differential # ... diagnosis #hematology ... #anemia

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