21 results
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
80-100 fL) • Bleeding ... (e.g. ... Renal Disease, Liver ... #Classification ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... : INR/PT, aPTT(liver ... changes), high MCV ... #Diagnosis #Causes ... #Workup #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... Deficiency • Disseminated ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Corpuscular Volume (MCV ... ) - Differential ... Myelodysplastic Syndromes ... #Causes #Hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... hemorrhage • Disseminated ... #diagnosis #differential ... #hematology #coagulation
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
: Alcohol use, Liver ... Myelodysplastic syndrome ... #differential # ... diagnosis #causes ... #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... Reduced liver synthesis ... Disseminated intravascular ... #diagnosis #differential ... #hematology #coagulation
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
, Liver diseases ... , Bleeding gastric ... Morphology #Atlas #key #diagnosis ... #differential # ... hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Disseminated Intravascular ... DIC • Severe Liver ... Disease: - Impaired ... #Coagulation #diagnosis ... #management #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
) • aPTT is prolonged ... mixing study (aPTT ... normal in mild cases ... hemophilia type (e.g ... #hematology