11 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... - Differential ... bilirubin • ↑ Reticulocytes ... #Anemias #Differential ... #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... aciduria, Drugs (e.g ... #MCV #Algorithm ... Diagnosis #hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (cell) volume (MCV ... acute blood loss, hemolysis ... of substrate (e.g ... #Workup #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... , MCV, MCH, MCHC ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Corpuscular Volume (MCV ... ) - Differential ... Diagnosis Algorithm ... • Secondary (e.g ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
) - Differential ... Diagnosis Algorithm ... • Bleeding • Hemolysis ... Chronic Disease (e.g ... #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Reticulocyte Production ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology ... #anemia #differential
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
) - Differential ... Diagnosis Algorithm ... +/- increased reticulocytes ... #Diagnosis #Algorithm ... #Causes #Hematology
General Approach to Anemia - Differential Diagnosis Framework
1) Check reticulocyte count to determine if hypo/hyper-proliferative
2) Exclude
- Differential ... hyper-proliferative 2) Exclude hemolysis ... haptoglobin) 3) Use MCV ... diagnosis #hematology ... #algorithm #reticulocyte
Autoimmune Hemolytic Anemia (AIHA)

WARM AHA
- Primary - Idiopathics
- Secondary
Infectious
 • Viral- HIV, EBV, HCV, HEV
 •
Anemia (AIHA) ... Viral- HIV, EBV, HCV ... Hematopoietic stem ... Diagnosis #Differential ... #Algorithm