116 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... Non-lmmune: • HELLP Syndrome ... Vasculitis • Infection ... Algorithm #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Myelofibrosis Infectious ... Non malignant hematologic ... effect following treatment ... following EtOH induced thrombocytopenia ... Iron deficiency anemia
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... microangiopathy: Thrombotic thrombocytopenic ... Hemolytic uremic syndrome ... differential #diagnosis #hematology ... #anemia
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
, Viral infections ... Dermatoses: Sweet Syndrome ... Gangrenosum, NEH T - Treatment ... fulminans/DIC, Thrombocytopenia ... MINTC #Mnemonic #dermatology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Iron-deficiency anemia ... Myelodysplastic syndrome ... Hemolytic uremic syndrome ... Thrombotic idiopathic thrombocytopenia ... #differential #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... : Chronic infections
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... SLE) - Viral infections ... Kasabach-Merritt syndrome ... APLS • Acute Infectious ... Differential #Diagnosis #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... /fevers • Thrombocytopenia ... Idiopathic • Infections ... Treatment: ... #oncology #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
infiltration (e.g ... . cancer, infection ... Marrow suppression (e.g ... G6PD deficiency), Infections ... Production #Index #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
procedures - Infection ... function test, ANA (e.g ... changes), high MCV anemia ... or if a primary hematologic ... Causes #Workup #hematology