8 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... risk-stratification • Risks: infection ... #MDS #Diagnosis ... #Management #treatment ... #hematology #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
underlying disease (eg ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Prednisone 5mg/kg ... Differential Diagnosis: Infection ... diagnosis #management #hematology ... #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(MDS) What? ... petechiae) • Frequent infections ... • Parvovirus infection ... #diagnosis #hematology ... #oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... if SSTI or port infection ... abdominal pain; full infectious ... ): - Hematologic ... decompression SVC
IDSA Recommendations for Prevention and Treatment of Pneumocystis Pneumonia (PCP) in HIV-AIDS
Indications for Initiating Primary Prophylaxis:
IDSA Recommendations ... Prevention and Treatment ... count monitoring (e.g ... PJP #jiroveci #opportunistic ... #infections #HIVAIDS
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... Triggers: ▪ Infections ... (often termed MAS-HLH ... underlying trigger: Infections ... Diagnosis #Management #Hematology