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diagnosis differential classification erythematosus rheumatology sle symptoms allergy causes hematology hypersensitivity reactions table types allergic autoantibodies bruising criteria definitions high
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... ) Blood (75%): Anemia ... normochromic nomocytic or haemolytic ... Thrombocytopenia #Lupus ... erythematosus #signs
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
Diagnostic Criteria - Systemic ... NEUROLOGIC - HEMOLYTIC ... ANEMIA - LEUKOPENIA ... the absence of hemolytic ... anemia #Diagnosis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Lymphadenopathies 7% - Hemolytic ... anemia 4% - Myositis ... Lupusreference #SLE #Systemic ... autoantibodies #signs
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... Autoimmune Diseases: • Systemic ... lupus erythematosus ... Antibody-mediated hemolysis
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
thrombocytopenia, Autoimmune Hemolytic ... anemia, Penicillin-induced ... complexes • Ex: Systemic ... Lupus Erythematosus
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
clubbing Clarkson/Systemic ... neuropathy) • Systemic ... • Coombs (-) hemolytic ... anemia due to cold ... IgG • Lupus anticoagulant
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
presentation of systemic ... lupus erythematosus ... Pericarditis #Symptoms #Signs ... #Presentation #comparison
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 Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
transfusion reaction, Haemolytic ... glomerulonephritis, Systemic ... lupus erythematosus ... classification #comparison
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
- SLE (systemic ... lupus erythematosus ... Non-immune - Haemolytic ... - Fanconi anaemia ... - Aplastic anaemia
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
leukocytosis, in vitro hemolysis ... Tubulointerstitial diseases: syßtemic ... lupus erythematosus ... ), sickle cell anemia ... amyloidosis, sickle cell anemia
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