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classification ana anca antibodies antibody antineutrophil antinuclear cerebritis champs cns cryoglobulinemia cryoglobulins diseases hypocomplementemia low mnemonic neurology sjogrens tafro thrombocytopenia
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... & renal involvement ... #Lupus #Erythematosus ... #SLE #Summary # ... diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... #lupus #Systemic ... #Diagnosis #Management ... #Summary #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Lupus Erythematosus ... (total 50, renal ... #differential # ... hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Lupus Erythematosus ... Demyelinating Syndrome ... #Lupus #Erythematosus ... #rheumatology # ... #management #treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... lupus erythematosus ... APLA/LAC: • Renal ... #Systemic #Lupus ... #Diagnosis #Rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
lupus erythematosus ... in drug-induced SLE ... polyangiitis without renal ... ANCA+ 30-60% • Renal-limited ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... lupus erythematosus ... (Renal involvement ... differential #diagnosis ... #rheumatology #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... • Autoimmune diseases ... • Low serum C4 complement ... lupus erythematosus ... classification #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... pulmonary and renal ... Differential Diagnosis ... #Differential #Diagnosis ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... cirrhosis: 3%-20% Renal ... Distal (Type I) renal ... #Rheumatology # ... Diagnosis #Management
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