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diagnosis differential management clinical algorithm signs causes pathophysiology neurology physicalexam video cardiology treatment nephrology table comparison rheumatology pulmonary msk ophthalmology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Reaction with Eosinophilia ... and Systemic Symptoms ... Symptoms: • The ... Eosinophilia 4 ... SinaiBmoreIMRes #DRESS #Syndrome
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment Stop offending agents: • List as allergies
Reaction with Eosinophilia ... and Systemic Symptoms ... (DRESS) Syndrome ... BrighamChiefs #DRESS #Syndrome
Restrictive Cardiomyopathy - Diagnosis and Causes Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema) Physical
↑ "Right Sided-Symptoms ... Fibrosis, Hyper-eosinophilc ... Syndrome, Endocardial
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... polyangiitis), EGPA (eosinophilic ... Pulmonary Renal Syndromes ... differential (check eosinophil ... or serologies + symptoms
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand 70 M vertebral osteomyelitis on vancomycin and cefepime for
reaction with eosinophilia ... and systemic symptoms ... antiphospholipid syndrome ... Churg-Strauss syndrome
Eosinophilic Esophagitis (EoE) - Spectrum of Response Non-response: • Histology: Persistent eosinophilia, ≥ 15 eos/hpf • Symptoms:
Eosinophilic Esophagitis ... Histology: Persistent eosinophilia ... : Persistent symptoms ... Histology: Reduced eosinophilia ... score < 2 #Eosinophilic
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy Mild Reaction - Itching, Minor rash
Stevens-Johnson syndrome ... nephritis, Drug rash eosinophilia ... systemic symptoms ... syndrome, Hemolytic
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... - Hepatitis, eosinophilic ... marrow-failure syndromes ... • Improve the symptoms
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... • (Peripheral eosinophilia ... develop leukostasis syndrome ... • Tumor lysis syndrome
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
hypereosinophilic syndrome ... • Eosinophilic ... Hyper-lgE (Job) syndrome ... ABPA), Gleich syndrome ... Infectious: Loeffler syndrome
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