15 results
Mixed Cellular Casts on Urine Microscopy

Degenerating mixed cellular cast - brightfield, unstained - from patient with
Mixed Cellular Casts ... on Urine Microscopy ... mixed cellular cast ... pneumococcal sepsis and AKI ... clinical #Urine #Microscopy
Crystal cast in patient with AKI and TLS on Urine Microscopy

Randy Luciano MD, PhD @RandyLucianoMD

#TLS #Crystal
Crystal cast in ... patient with AKI ... and TLS on Urine Microscopy ... #casts #crystalluria ... #Urine #Microscopy
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... fresh at time of microscopy ... tubular injury • Crystals ... - Some crystals ... individuals; “abnormal” crystals
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Kidney Injury (AKI ... Epithelial cell casts ... Obstruction • Cast ... myeloma) • Urate crystals ... polyangiitis /microscopic
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Kidney Injury (AKI ... cases are caused ... Assess UA w/ microscopy ... for WBCs, RBCs, casts ... , crystals, protein
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
sensitive) • AKI ... , AKD, rapidly progressive ... sterile pyuria, WBC casts ... eosinophiluria, microscopic ... proteinuria, granular casts
Trichomonas on Urine Microscopy

Trichomonas organisms adjacent to mixed cellular cast containing WBC's, tubular epithelial cells, and
Trichomonas on Urine Microscopy ... mixed cellular cast ... from patient with AKI ... Trichomonas #Urine #Microscopy
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Kidney Injury (AKI ... Light chain (LC) cast ... ifosfomide • Crystal ... bevacizumab (VEGFi), TKi ... Kidney #Injury #AKI
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
white blood cell casts ... renal tubular cell casts ... or pigmented casts ... Intrarenal: stones, crystals ... Kidney #Injury #AKI
Urine Microscopy - Urinary Sediment Examination Instructions
Preparation of the urine for microscopic examination:
 • Clean catch
up by cells or casts ... Ill stain) and crystals ... RBC's, lipids, crystals ... protein matrix of casts ... identification of lipids, crystals