15 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Diagnosis: >3 symptoms ... initiation • Differential ... #diagnosis #management ... #hematology #oncology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... ongoing ↑ LFTs or symptoms ... Idiosyncratic #differential ... #Diagnosis #Management ... gastroenterology #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
postpartum): • Initial symptoms ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... #Pregnancy #hepatology ... obgyn #diagnosis #management
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Contrast Enhanced Ultrasound ... Lesions #Hepatic #Ultrasound ... Contrast #CT #MRI #POCUS ... #radiology #differential ... table #appearance #hepatology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... if neutropenic fever ... Anemia #diagnosis #management ... #treatment #hematology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Malar rash 40% - Fever ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
gas on hepatic ultrasound ... reflection on the differential ... portal #venousgas #ultrasound ... #hepatology #liver ... #pocus #clinical
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... , signs, and complications ... transformation into AML ... PV #Diagnosis #Management ... Summary #treatment #hematology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... /signs should be ... mellitus; USS, ultrasound ... Abnormal #Algorithm #Hepatology ... #Differential #
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Diagnosis: HLH signs ... and symptoms can ... following: • Fever ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology