3070 results
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
could be multiple factors ... Causes include : ... Pre-analytical cause ... Decreased factor ... aPTT #Prolonged #Causes
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... Decreased factor ... Factor consumption ... aPTT #Prolonged #Causes
Causes of Falls in the Elderly - Differential Diagnosis Algorithm
- Intrinsic Factors - 
Presyncope / Syncope
Causes of Falls ... Algorithm - Intrinsic Factors ... - Extrinsic Factors ... Diagnosis #Algorithm #Causes
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
a coagulation factor ... Von Willebrand factor ... Von Willebrand factor ... inhibitors - factor ... discern these causes
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Congenital • Factor ... Deficiency • Factor ... Diagnosis #Algorithm #Causes
Review of the Coagulation Cascade
Traditional Model:
 • Parallel extrinsic and intrinsic pathways.
Contemporary Model:
 • 4 key
activated clotting factor ... Initiation phase caused ... by tissue factor's ... intrinsic X-ase; factors ... cross-linked by Factor
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Consumption of Clotting Factors ... Reduced levels of factors ... Exposure → Tissue factor ... Treat primary cause ... Coagulation #diagnosis #causes
When to Evaluate for Secondary Causes of Hypertension
1. Severe or resistant HTN
2. Acute rise/lability in BP
3.
for Secondary Causes ... Age <30 w/o risk factors ... #Hypertension #causes
Causes of Purpura - Differential Diagnosis
Disruption in Vascular Integrity: 
 • Trauma, Infection, Vasculitis, Drug induced
Causes of Purpura ... dysfunction • Clotting factor ... nonpalpable #palpable #Causes
Causes of Intrauterine Growth Restriction / Small for Gestational Age - Differential Diagnosis Algorithm
Fetal Factors:
 -
Causes of Intrauterine ... Algorithm Fetal Factors ... 45X Placental Factors ... Rare) Maternal Factors ... Diagnosis #Algorithm #Causes