2568 results
REBEL Review 79: Treatment of Hemophilia 

Walkina Out of Pt Room, You Should Know... 
1. Type
Factor Activity ... Type of Factor ... ) Units of Factor ... #factor9 #factorviii ... #factorix
Factor VIII synthesis - Normal, Haemophilia A and Von Willebrand Disease

Normal - vWF carrier protein protects
Factor VIII synthesis ... #FactorVIII #synthesis
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... could be multiple factors ... Decreased factor ... Factor consumption ... Causes #diagnosis #differential
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... a coagulation factor ... Von Willebrand factor ... Von Willebrand factor ... Bruising #Hemostasis #Differential
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Contact pathway factors ... Decreased factor ... Factor consumption ... Factor X deficiency ... Causes #diagnosis #differential
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
to coagulation factors ... PF-3, platelet factor
Approach to a Positive (+) Rheumatoid Factor (RF)
(+) RF does not always = RA
Rheumatic disorders:
 •
(+) Rheumatoid Factor ... #Rheumatoid #Factor ... rheumatology #laboratory #differential
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
either a clotting factor ... inhibitor of normal factor ... generally only require factors ... Patient has a factor ... Patient has a factor
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... Acquired Risk Factors ... Thrombophilia: - Factor ... cardiovascular risk factors ... pathophysiology #hematology #differential
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
von Willebrand factor ... normal Individual factor ... with relevant factor ... Serious: 100% factor ... Moderate: 50% factor