27 results
Feedback Loop: Prolactin (PRL)
 • PRL levels exhibit diurnal, menstrual, and age-related variation
 • TRH has
Feedback Loop: Prolactin ... Prolactin #PRL #FeedbackLoop ... pathophysiology #pituitary
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth ... GrowthHormone #GH #FeedbackLoop ... pathophysiology #pituitary
Causes of Primary and Secondary Amenorrhea - Differential Diagnosis Algorithm
Primary Amenorrhea - No onset of menarche
Causes of Primary ... Diagnosis Algorithm Primary ... • Central - Pituitary ... estrogen: • Pituitary ... Obstruction #Primary
Menstrual Cycle Physiology: The Hypothalamic-Pituitary-Ovarian Axis
Estrogen, when released:
 • Negatively feeds back on the hypothalamus and
The Hypothalamic-Pituitary-Ovarian ... hypothalamus and anterior pituitary ... hypothalamus and anterior pituitary ... endocrinology #feedback
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained

Around Day 14, estrogen exerts sudden +++ positive feedback
sudden +++ positive feedback ... on the anterior pituitary ... negative to positive feedback
Nipple Discharge - Galactorrhea - Differential Diagnosis Algorithm

↑ TSH - Primary hypothyroidism
↑ ß-HCG - Pregnancy
↑ Creatinine
Algorithm ↑ TSH - Primary ... failure MRI of pituitary
Breast Discharge - Differential Diagnosis Algorithm
High Prolactin + Normal TSH
 • Microprolactinoma
 • Steroid Hormone Intake
Normal/ Low TSH • Pituitary ... Inhibition • Pituitary ... + High TSH • Primary
Adrenal Insufficiency - Differential Diagnosis Workup Algorithm
Primary Adrenal Insufficiency:
 • Autoimmune primary adrenal insufficiency
 • Adrenoleukodystrophy,
Workup Algorithm Primary ... • Autoimmune primary ... ACTH-deficiency • Combined pituitary
Sellar / Pituitary Mass - Differential Diagnosis Algorithm
Adenoma - Primary Anterior Pituitary
 - Secreting
Sellar / Pituitary ... Algorithm Adenoma - Primary ... Anterior Pituitary ... #SellarMass #Pituitary
Multiple Endocrine Neoplasia Type 1 (MEN 1)
 • Primary Hyperparathyroidism
 • Pituitary Adenoma
 • Pancreatic /
Type 1 (MEN 1) • Primary ... Hyperparathyroidism • Pituitary