10 results
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS)
Mayo Clinic Risk Stratification Model. CBC,
Suggested algorithm ... for follow-up of monoclonal ... significance (MGUS) Mayo Clinic ... #monoclonal #gammopathy ... diagnosis #management #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Monoclonal Gammopathy ... of Clinical Significance ... capillary leak syndrome ... #Gammopathy #Clinical ... Differential #Diagnosis #hematology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
Suggested algorithm ... whom there are no clinical ... features concerning ... #monoclonal #gammopathy ... diagnosis #management #hematology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Gammopathy of Undetermined ... Significance (MGUS) Fracture ... rituximab (in clinical ... #Gammopathy #Complications ... #diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Idiopathic monoclonal ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... gammopathy of undetermined ... hemolytic #anemia #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
it represents a monoclonal ... Causes of Monoclonal ... changes (POEMS syndrome ... gastric tumors • Hematology ... differential #diagnosis #hematology
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... Relapsing-remitting course +++ Clinical ... features: 1. ... Monoclonal gammopathy ... timeline #treatment #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... Features: • Synovitis ... Rule out other causes ... #Rheumatology # ... diagnosis #management #Dermatology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm
INDICATIONS FOR TESTING:
 • Vascular thrombosis
Antiphospholipid Syndrome ... Hypercoagulable Workup Algorithm ... - 1 or more clinical ... maternal chromosomal causes ... #diagnosis #hematology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Helpful Clinical ... Features in Evaluating ... Marfan syndrome, ... Disorders #History #peds ... pediatrics #diagnosis #hematology