11 results
diagnosis hematology management dermatomyositis gammopathy mgus activation antimda5 antimda5dm antinxp2 antinxp2dm antiphospholipid apls biopsy bleeding capillary clarksons dermatologic differential disease
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... capillary leak syndrome ... • Schnitzler syndrome ... #Gammopathy #Clinical ... Differential #Diagnosis #hematology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
Suggested algorithm ... patients with monoclonal ... whom there are no clinical ... features concerning ... diagnosis #management #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Maculopapular rash ... • Goodpasture syndrome ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... Petechial or purpuric rash ... Diagnosis #Management #Hematology ... #Rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... auricular papules Clinical ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... Features: • Synovitis ... Rule out other causes ... #Rheumatology # ... diagnosis #management #Dermatology
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... Relapsing-remitting course +++ Clinical ... features: 1. ... Monoclonal gammopathy ... timeline #treatment #rheumatology
Symmetrical Drug-Related Intertriginous and Flexural Exanthema (SDRIFE) 49M +burning rash groins/buttocks (pic in next thread) x 1d.
MCQ highlights a case ... gluteal areas Other features ... known as baboon syndrome ... #clinical #photo ... #dermatology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome ... Hypercoagulable Workup Algorithm ... - 1 or more clinical ... maternal chromosomal causes ... #diagnosis #hematology
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Helpful Clinical ... Features in Evaluating ... Marfan syndrome, ... Disorders #History #peds ... pediatrics #diagnosis #hematology
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