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algorithm rheumatology causes management clinical dermatology oncology radiology signs secondary classification disorders erythematosus lupus mri sle vasculitis disease generalized infectiousdiseases
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Diagnosis Algorithm ... Features of ... : • Symptoms: ... B-symptoms, bruising ... hepatomegaly • Labs: anemia
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diagnosis Congenital ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Autoimmune Diseases: • Systemic ... #Diagnosis #Hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Demyelinating syndromes ... ) Blood (75%): Anemia ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Vascular Joint Pain - Differential Diagnosis Algorithm - Constant Pain (Ischemia) - Acute Onset -
Diagnosis Algorithm ... • Sickle Cell Anemia ... Marfan's Syndrome ... Vascular #JointPain #MSK ... #Differential #
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Joint Disorders - Differential ... Diagnosis Algorithm ... arthritis - (Reiter’s syndrome ... should have other symptoms ... Joint #Disorders #msk
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Iron deficiency anemia ... • Nephrotic syndrome ... #Secondary #dermatology ... #Differential # ... Diagnosis #Algorithm
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS) - Differential ... Diagnosis Neurologic-Centered ... capillary leak syndrome ... • Schnitzler syndrome ... #Diagnosis #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Diagnosis Algorithm ... renal failure/uremia ... Myelodisplastic syndrome ... #generalized #dermatology ... Diagnosis #Algorithm
Vertebral Body Abnormalities A sheet of common (and uncommon) vertebral body findings, because a completely “normal” spine
Morquio Syndrome ... Abnormalities #Radiology ... #MSK #Pathology ... Anomalies #Spine #Diagnosis ... Vertebrae #diseases #differential
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... with leukopenia, anemia ... Histopathologic features ... #Diagnosis #Management ... #Hematology #Rheumatology
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