22 results
Iron Deficiency in Heart Failure - Diagnosis and Treatment Algorithm
Diagnosis: Ferritin <100 ng/mL (absolute ID) OR
Diagnosis and Treatment ... with TSAT <20% (functional ... #CHF #HFrEF #heartfailure ... #diagnosis #management ... #algorithm #cardiology
Algorithm for screening/diagnosis and treatment/follow‐up of iron deficiency in patients with chronic heart failure. Hb, haemoglobin;
reduced ejection fraction ... #Management #Diagnosis ... #HFrEF #sCHF #HeartFailure ... #Cardiology #Indications ... #Treatment
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
with TSAT <20% (functional ... ID) Treatment - ... #CHF #HFrEF #heartfailure ... #diagnosis #management ... #cardiology
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
, treatment with ... cardiovascular causes ... hospitalization for the management ... Spironolactone #HFpEF #dCHF ... #Cardiology #EBM
Krabbe Disease 

Check out this interesting case of Krabbe disease, a rare genetic leukodystrophy. Diagnosis was
this interesting case ... testing and expedite treatment ... leukodystrophy w/ deficiency ... • Dec NAA, inc Cho ... #Radiology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... hemopathies, solid cancers ... mevalonate kinase deficiency ... Disease #diagnosis #management ... #treatment #rheumatology
Mallet Finger
Absence of a fracture does NOT exclude Mallet finger, the extension function of the DIP
the extension function ... joint needs to be clinically ... Finger deformity caused ... 1 week MH/CCF ... Mallet #Finger #Radiology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess Etiology ... Lung Abscess - Clinical ... foreign body, cancer ... #differential #causes ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... B-LNH), solid cancers ... Cellular immune deficiency ... Treatment: • ... Lymphohistiocytosis #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
specific loss-of-function ... Aplastic Anemia Clinical ... and petechiae Causes ... aplastic anemia Treatment ... hematology #diagnosis #management