19 results
diagnosis oncology algorithm management cold hodgkins leukemia lymphoma reticulocyte agglutinin aplastic autoimmune calculation causes chronic classification cll common cvid deficiency
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Hemolytic Anemia ... Complement-mediated • Etiology ... Complement-mediated • Etiology ... #Anemia #hematology ... #diagnosis #comparison
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Bleed • Hemolysis ... Inflammation • Cancer ... #Differential # ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... deficiency • Fanconi’s anemia ... telomeropathy Cancer ... Antibody-mediated hemolysis ... #Diagnosis #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
infiltration (e.g. cancer ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology ... #anemia #differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... , deficiency anemia ... Malignancy: Metastatic cancer ... Diagnosis #Algorithm #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... #Diagnosis #hematology ... #nonpalpable #dermatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... • Symptoms of anemia ... anemia • Cold ... younger pts) Differential ... #anemia #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... Autoimmune diseases • Clinical ... #NonHodgkins #comparison ... #differential # ... hematology
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
pregnant have hemolytic ... anemia, or psoriasis ... with leading to a functional ... deficiency #FolicAcid #differential ... #diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... specific loss-of-function ... Clinical Presentation ... #oncology #hematology
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