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diagnosis hematology differential management algorithm treatment causes clinical anemia liver pathophysiology cirrhosis pharmacology workup gastroenterology oncology syndrome table thrombocytopenia anticoagulation
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG) SAAG ≥ 1.1: - Ascitic protein
protein ≤ 2.5 g/ ... protein ≥ 2.5 g/ ... albumin #gradient #hepatology
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
injury (≥ 1B) - 1 g/ ... days then 20-40 g/ ... Cirrhosis #treatment #hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
hypertension (SAAG > 1.1 g/ ... conditions (SAAG < 1.1 g/ ... Myxedema (SAAG 2 1.1 g/ ... Peritoneum (SAAG < 1.1 g/ ... #differential #hepatology
Hepatic Hydrothorax • Presents as right sided in 85% of cases • Fluid studies:
gradient > 1.1 g/ ... - Protein <2.5 g/ ... Hydrothorax #diagnosis #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
gradient (>1.1 g/ ... gradient (<1.1 g/ ... Differential #Diagnosis #hepatology
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
response to 1 g/ ... HRSAKI #HRSNAKI #hepatology
Clinical Diagnosis of Autoimmune Hepatitis - Onset of jaundice within prior 8 weeks - Ongoing consumption
) or 60 (male) g ... Hepatitis #Diagnosis #Hepatology
Clinical diagnosis of Alcoholic Hepatitis (AH) • Onset of jaundice within prior 8 weeks • Ongoing
) or 60 (male) g ... Hepatitis #AH #hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Ascites protein 22.5 g/ ... Diagnosis #causes #hepatology
Ascites - Diagnosis and Management Summary Paracentesis studies: cell count + differential, albumin, protein, culture • Serum-ascites-albumin-gradient
(SAAG): > 1.1 g/ ... If > 2.5 g/dL, consider ... Management #Summary #Hepatology
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