27 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
is rare in DIL, SCLE-DIL ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Bacterial or viral infection ... Amyloidosis • Scalp ... Cardiomyopathies - Viral infection ... #joint #pain #differential ... #diagnosis #rheumatology
Hematuria in Post-Renal Transplant Patient
Prevalence up to 12% in the postrenal transplant patient
 • Bacterial: Escherichia
: Secondary to infections ... Goodpasture's syndrome, SLE ... Renal #Transplant #differential ... #blood #urine #management ... #treatment #nephrology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • Infectious ... Disease #diagnosis #management ... #treatment #rheumatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
rheumatoid arthritis, SLE ... life-threatening Differential ... Miller Fischer and PCB ... precipitated by: Drugs, infection ... Gravis #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... initiation • Differential ... Diagnosis: Infection ... fluid overload, PCC ... APML #diagnosis #management
Capnocytophaga
Pathogen: Capnocytophaga
 • 9 species, C. canimorsus responsible for the majority of infections
 • Gram-negative rod,
the majority of infections ... ), Malignancy, SLE ... specificity of PCR ... infectiousdiseases #diagnosis #management ... #treatment
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Diagnosis and Management ... Statins), ETOH Infection ... levels > 8mg/dL See ... #Diagnosis #Management
Helicobacter Pylori (H. pylori) Infection - Diagnosis and Management - GrepMed Handbook
Presentation: Dyspepsia / Peptic Ulcer
Pylori (H. pylori) Infection ... (IgG) - cannot differentiate ... past infection ... flagyl 500mg TID if PCN-allergy ... #Treatment #quadruple