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hematology syndrome causes lupus oncology disease druginduced infectiousdiseases neurology signs summary symptoms thrombocytopenia abscess activation adultonset apml arteritis behcet blood
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Autoimmune diseases: SLE ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
is rare in DIL, SCLE-DIL ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Bacterial or viral infection ... Amyloidosis • Scalp ... Cardiomyopathies - Viral infection ... #joint #pain #differential ... #diagnosis #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • ... Infectious: Mycoplasma ... #management #treatment ... #rheumatology
Hematuria in Post-Renal Transplant Patient Prevalence up to 12% in the postrenal transplant patient • Bacterial: Escherichia
: Secondary to infections ... Goodpasture's syndrome, SLE ... #diagnosis #kidney ... #blood #urine #management ... #treatment #nephrology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... initiation • Differential ... Diagnosis: Infection ... fluid overload, PCC ... #management #hematology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... life-threatening Differential ... myasthenia Diagnosis ... precipitated by: Drugs, infection ... #management #neurology
Capnocytophaga Pathogen: Capnocytophaga • 9 species, C. canimorsus responsible for the majority of infections • Gram-negative rod,
the majority of infections ... ), Malignancy, SLE ... specificity of PCR ... Treatment: • 50% ... #management #treatment
Helicobacter Pylori (H. pylori) Infection - Diagnosis and Management - GrepMed Handbook Presentation: Dyspepsia / Peptic Ulcer
Pylori (H. pylori) Infection ... (IgG) - cannot differentiate ... past infection ... flagyl 500mg TID if PCN-allergy ... #Management #Treatment
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Rhabdomyolysis - Differential ... Diagnosis and Management ... Statins), ETOH Infection ... levels > 8mg/dL See ... #Diagnosis #Management
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