12 results
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
/dL or CC < 40 ml ... Causes of false- ... amyloidosis Other causes ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear Antibody ... scleroderma) - Anti-Scl ... anti-topoisomerase antibody ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... Smith, Sm/RNP, Scl ... #Antinuclear #Antibody ... #differential #diagnosis ... #rheumatology
Moccasin-variety Tinea Pedis 
70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Moccasin-variety Tinea Pedis ... Diagnosis? ... dermatophytes cause ... type #clinical #photo ... #foot #dermatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
(HCV) • CLL & MBL ... Thrombosis in vascular beds-renal ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Overview: ALL, CML ... involvement CML ... -> AML: Blast crises ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
classical HL (MCHL ... lymph node biopsy (diagnostic ... Hodgkins #lymphoma #diagnosis ... classification #hematology ... #oncology #management
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antinuclear Antibody ... Smith, Sm/RNP, Scl ... #Antinuclear #Antibody ... #differential #diagnosis ... #rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Myelogenous Leukemia (CML ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Symmetrical Drug-Related Intertriginous and Flexural Exanthema (SDRIFE)

49M +burning rash groins/buttocks (pic in next thread) x 1d.
The MCQ highlights ... a case of symmetrical ... thighs, inguinal, gluteal ... rash #clinical #photo ... #dermatology