18 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
Acute promyelocytic ... overt cytoplasmic granules ... , and Auer rods. ... these features in ... most cases, even
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
a linear red "Auer ... of crystallized granules ... are typical for acute ... most prevalent in ... #Blood #Smear #Microscopy
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Algorithmic Approach ... to Acute Interstitial ... eosinophiluria, microscopic ... tubular proteinuria, granular ... casts/RTE; blend
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of acute ... a variety of acute ... ) • Granular Casts ... #Urine #Microscopy
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... tubular cells - Acute ... fresh at time of microscopy ... renal disease • Granular ... protein indicating acute
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
abundant cytoplasmic granules ... diagnosed with acute ... , Auer rods in neutrophils ... acute myeloid leukemia ... #Blood #Smear #Microscopy
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
nonspecific; seen in ... concentrated urine Granular ... Muddy-brown" heme-granular ... in acute tubular ... #Differential #Microscopy
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Differential Diagnosis Algorithm ... in creatinine by ... Epithelial cell casts ... Obstruction • Cast ... polyangiitis /microscopic
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Simplified Approach to Acute ... PROBLEM ~80% of AKI cases ... Assess UA w/ microscopy ... for WBCs, RBCs, casts ... LorinskyMD #AKI #Acute
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... repeat testing • Acute ... unilateral flank pain ... proteinuria, RBC casts ... Hematuria #Diagnosis #Algorithm