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management differential algorithm anemia causes hemolysis iron rbc workup aplastic atlas blood chf chronic classification extravascular heartfailure intravascular leukemia lymphocytic
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... organ or stem cell ... • Severe B12 deficiency ... #differential #diagnosis ... #hematology #hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) (e.g. lupus, CLL ... G6PD deficiency) ... #differential #diagnosis ... #hematology #anemia
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
Heinz Bodies: G6PD deficiency ... Thalassemia, Sickle cell ... , MDS #RBC #Inclusions ... #Bodies #diagnosis ... #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential Diagnosis ... • Sickle cell ... • PK deficiency ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential Diagnosis ... -100): • Non-hemolytic ... anemia, CKD • Hemolytic ... Reticulocytosis, MDS ... #hematology
Diffuse large B cell lymphoma (DLBCL) - Management and Treatment Algorithm By Matthew Ho, MD PhD @MatthewHoMD #Diffuse
Diffuse large B cell ... Management and Treatment ... By Matthew Ho, MD ... #Algorithm #oncology ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Consider sickle cell ... #Differential #Diagnosis ... Algorithm #workup #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... , deficiency anemia ... Rebound effect from treatment ... #Algorithm #hematology
Iron Deficiency in Heart Failure - Diagnosis and Treatment Algorithm Diagnosis: Ferritin <100 ng/mL (absolute ID) OR
and Treatment Algorithm ... NYHA class II and Ill ... patients with HFrEF ... #algorithm #cardiology ... #treatment #guidelines
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Liver Disease, MDS ... Microangiopathic Hemolytic ... Cold autoimmune hemolytic ... #differential #diagnosis ... #hematology #microscopy
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