7 results
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD
EMPA-REG OUTCOME - Empagliflozin lowered CV events
inhibitors in CVD ... HF outcomes in HFrEF ... on GDMT, with or ... HF outcomes in HFrEF ... SGLT2 #inhibitors #EBM
Stages in the development of HF and recommended therapy by stage. ACEI indicates angiotensin-converting enzyme inhibitor;
ejection fraction; GDMT ... heart failure; HFpEF ... ejection fraction; HFrEF ... #HeartFailure #Staging ... Algorithm #Management #Cardiology
Guideline-Directed Medical Therapy (GDMT) in HFrEF and CKD

 • Class I pillars of HFrEF GDMT across
) in HFrEF and CKD ... used in HFrEF: ... Statins, Thiazides ... #CKD #HFrEF #management ... #pharmacology #cardiology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... functional ID) Treatment ... mortality and CV ... deficiency #CHF #HFrEF ... diagnosis #management #cardiology
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
ejection fraction, treatment ... Spironolactone #HFpEF ... #dCHF #Cardiology ... #EBM #VisualAbstract ... #Trial
Heart Failure with Preserved Ejection Fraction: Management Principles

General Therapeutic Principles:
Reduce the congestive state 
 - Caution
sinus rhythm in atrial ... hypertension, pulmonary ... #Management #Cardiology ... #HFpEF #dCHF #Diastolic ... #Treatment #HeartFailure
HFpEF and CAD Management Algorithm
1. Consider revascularization based on current guidelines for CAD and HFpEF*
2. Statins:
HFpEF and CAD Management ... and HFpEF* 2. ... Statins: all patients ... Enroll in HFpEF ... #HFpEF #CAD #Management