254 results
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
Castleman's Disease ... • unicentric, HHV8 ... associated with Castleman's ... Plasmablastic subtype is HHV8 ... myeloma, POEMS) HHV8
HHV8/KSHV-reIated diseases: From Cellular Proliferation to Hyperinflammation
Kaposi sarcoma (KS):
 • Target organs: Ubiquitous (cutaneous and mucosal
HHV8/KSHV-reIated ... Light chain: - HHV8 ... + Multicentric Castleman ... de Fremont #HHV8
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis
 • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Causes of Fever ... vasculitis to cause ... Hypothalamic dysfunction, Castleman ... Differential #Diagnosis #causes
Lymphadenopathy - Differential Diagnosis Algorithm
Localized: 
 • Cervical: EBV, CMV, HIV, Toxo, TB, Lymphoma, Head /
Miscellaneous: Castleman's ... Diagnosis #Algorithm #Causes
IDSA Recommendations for Preventing and Treating HHV-8 Diseases—Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL), Multicentric Castleman’s
Preventing and Treating HHV ... , Multicentric Castleman ... activity against HHV ... adjunctive therapy #HHV8 ... KaposiSarcoma #Castlemans
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Causes of false- ... amyloidosis Other causes ... POEMs syndrome, Castleman's
Internal Jugular Vein Rouleaux Flow on POCUS

Amazing video of a dilated IJV showing Rouleaux flow. Whenever
POCUS Amazing video ... significantly, it causes ... echogenic as in this case ... for underlying cause
Pemberton's Sign caused by a Retrosternal Thyroid Goiter

Elevating the arms causes the previously flat neck veins
Pemberton's Sign caused ... Elevating the arms causes ... PhysicalExam #clinical #video
MIAMI Mnemonic for Differential Diagnosis of Lymphadenopathy
Malignancies
 - Kaposi sarcoma, leukemias, lymphomas, metastases, skin neoplasms
Infections
 -
node hyperplasia (Castleman ... sarcoidosis Iatrogenic causes
Transplant Infections Timeline
Pre-transplant:
 • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut)
 • Viruses: HSV (reactivation)
Engraftment:
reactivation), HHV ... differential #diagnosis #causes