340 results
Clinical Manifestations of Human Herpes Viruses (HHV)

Herpes simplex virus 1	HSV-1	Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
Herpes Viruses (HHV ... herpes virus 6 HHV ... herpes virus 7 HHV ... herpesvirus 8 HHV ... Herpes #Viruses #HHV
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
and Associated Syndromes ... • unicentric, HHV8 ... Plasmablastic subtype is HHV8 ... Pathogenesis "IL6 syndrome ... myeloma, POEMS) HHV8
Infection-Related Cancers
Viruses:
 • HPV - Cervical, anogenital, head and neck, skin cancer
 • HTLV-1 - Adult
Cancers Viruses: • HPV ... T-cell Leukemia • HIV ... cell carcinoma • HBV ... / HCV - Hepatocellular ... carcinoma • HHV
HHV8/KSHV-reIated diseases: From Cellular Proliferation to Hyperinflammation
Kaposi sarcoma (KS):
 • Target organs: Ubiquitous (cutaneous and mucosal
HHV8/KSHV-reIated ... • Association HIV ... Light chain: - HHV8 ... • Association HIV ... de Fremont #HHV8
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
• Infectious: HAV ... , HCV, HEV, EBV, ... HSV, CMV • Neoplasm ... Vascular: Budd-chiari syndrome ... Sinusoidal obstruction syndrome
Kaposi Sarcoma Herpes Virus (KSHV)

By Dr. Sara Dong @swinndong via #IDFellowCase
#ID  #Infectious Diseases  #Infections
#Differential
Diagnosis #KSHV #HHV
Transplant Infections Timeline
Pre-transplant:
 • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut)
 • Viruses: HSV (reactivation)
Engraftment:
gut) • Viruses: HSV ... airways) • Viruses: HSV ... reactivation), HHV
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... Indications Treatment ... ), normal ALT Treatment ... history of HCC Treatment ... #Treatment #Indications
Genital Herpes Simplex - CDC 2021 Treatment Guidelines
Recommended Regimens:
 • First clinical episode of genital herpes
Simplex - CDC 2021 Treatment ... genital herpes (HSV ... genital herpes (HSV ... in persons with HIV ... #CDC #CDC2021 #Treatment
IDSA Recommendations for Preventing and Treating HHV-8 Diseases—Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL), Multicentric Castleman’s
Preventing and Treating HHV ... activity against HHV ... recommended for KS treatment ... adjunctive therapy #HHV8 ... IDSA #Prevention #Treatment