416 results
KSHV Inflammatory Cytokine Syndrome (KICS)

By Dr. Sara Dong @swinndong  via #IDFellowCase
#ID  #Infectious Diseases
KSHV Inflammatory ... Ddx #Diagnosis #KSHV ... #HHV #KICS #Kaposi
KSHV Inflammatory Cytokine Syndrome (KICS)
Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
KSHV Inflammatory ... 3) Evidence of KSHV ... activity - Elevated KSHV ... #Inflammatory # ... diagnosis #management #hhv8
Kaposi Sarcoma Herpes Virus (KSHV)

By Dr. Sara Dong @swinndong via #IDFellowCase
#ID  #Infectious Diseases  #Infections
#Differential
Herpes Virus (KSHV ... Ddx #Diagnosis #KSHV ... #HHV #lymphoproliferative
HHV8/KSHV-reIated diseases: From Cellular Proliferation to Hyperinflammation
Kaposi sarcoma (KS):
 • Target organs: Ubiquitous (cutaneous and mucosal
HHV8/KSHV-reIated ... Light chain: - HHV8 ... de Fremont #HHV8 ... comparison #diagnosis #kshv
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
• unicentric, HHV8 ... Plasmablastic subtype is HHV8 ... myeloma, POEMS) HHV8
Clinical Manifestations of Human Herpes Viruses (HHV)

Herpes simplex virus 1	HSV-1	Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
Herpes Viruses (HHV ... herpes virus 6 HHV ... herpes virus 7 HHV ... herpesvirus 8 HHV ... Herpes #Viruses #HHV
IBD - Assessment of Lack of Response (sLOR) - Differential Diagnosis
Non-inflammatory mechanisms:
 • IBS
 • Fibrostenotic
Diagnosis Non-inflammatory ... SIBO, lactose) Inflammatory ... • Ischaemic Inflammatory ... clearance - Inflammatory ... Diagnosis #Causes #Inflammatory
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
production of pro-inflammatory ... Virus (EBV, CMV, HHV8
Seronegative Inflammatory Arthritis - Differential Diagnosis
 • Seronegative Rheumatoid Arthritis 
 • Infectious Arthritis: Viral, Bacterial,
Seronegative Inflammatory ... Still's Disease, Inflammatory ... #Seronegative #Inflammatory
Web chart of etiologies related to inflammatory head and neck masses.

#pediatrics #peds #differential #causes #pearls #head
etiologies related to inflammatory ... #neck #masses #inflammatory