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Transplant Infections Timeline Pre-transplant: • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut) • Viruses: HSV (reactivation) Engraftment:
Transplant Infections ... Timeline Pre-transplant ... reactivation), HHV ... Protozoa: T. gondii #Transplant ... differential #diagnosis #causes
Graft-Verus-Host Disease (GVHD) - Quick Reference Sheet Multisystem disorder that is a common complication of allogeneic hematopoietic
hematopoietic cell transplant ... when immune cells transplanted ... recognize the transplant ... reaction that causes ... disease in the transplant
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
of solid-organ transplants ... Risk Factors by transplant ... • Solid organ transplant ... Type of organ transplanted ... to 50% of PTLD cases
Castleman's Disease and Associated Syndromes HYALINE VASCULAR VARIANT • unicentric, HHV8-ve, children and young. • Hyalinized vessels
• unicentric, HHV8 ... Plasmablastic subtype is HHV8 ... myeloma, POEMS) HHV8
Infections in Immunocompromised Patients - Differential Diagnosis Summary Innate Immunity: • Neutropenia • Phagocytic Deficiencies • Complement
• Solid Organ Transplant ... Allogeneic Stem Cell Transplant ... Deeksha Jandhyala @transplantID
Drugs Causing Acute Pancreatitis Class Ia: The medications in which there was a rechallenge and other causes
rechallenge and other causes ... out other common causes ... Class II: Cases ... and atleast4 case ... #Pancreatitis #Causes
Common causes of post-Transplant Diarrhea • Bacterial: Clostridium difficile, Campylobacter spp., Salmonella spp., Bacterial overgrowth, Aeromonus
Common causes of ... post-Transplant ... Malabsorption #Transplant ... #differential #causes
HHV8/KSHV-reIated diseases: From Cellular Proliferation to Hyperinflammation Kaposi sarcoma (KS): • Target organs: Ubiquitous (cutaneous and mucosal
HHV8/KSHV-reIated ... Light chain: - HHV8 ... de Fremont #HHV8
Clinical Manifestations of Human Herpes Viruses (HHV) Herpes simplex virus 1 HSV-1 Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
Herpes Viruses (HHV ... herpes virus 6 HHV ... herpes virus 7 HHV ... herpesvirus 8 HHV ... Herpes #Viruses #HHV
ID Ddx: Diarrhea in a transplant recipient - Bacterial: C.diff, Campy, Salmonella, Aeromonas, E.coli - Viral: CMV, noro,
Diarrhea in a transplant ... Diagnosis #Diarrhea #Transplant ... #TxID #SOT #Causes
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