18 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus (SLE ... erythematosus (SLE ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... pattern: - SLE ... ARUPLabs #ANA #Antinuclear ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... Malar rash • SLE ... dermatology #joint #pain ... #skin #rashes #differential ... #diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... assay (IFA) is the main ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology ... #diagnosis #differential
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Vasculitis (e.g., PAN ... conditions #joint #pain ... #differential # ... diagnosis #rheumatology
Pulmonary Embolism on POCUS Echocardiogram

Mid 30's female with chest pain/dyspnea.  Triage EKG (no prior).
Embolism on POCUS Echocardiogram ... female with chest pain ... Differential/diagnosis ... See thread for POCUS ... Embolism #POCUS #Echocardiogram
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
of Bone/Joint Pain ... dz difficult to see ... • Differentiate ... SickleCell #Disease #differential ... diagnosis #causes #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... - Autoimmune Rheumatologic ... arthritis • SLE ... Symmetrical: • RA • SLE ... #Differential #
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody ... AMA Speckled: • SLE ... ARUPLabs #ANA #Antinuclear ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
Inflammatory joint pain ... and fingers, or pain ... the face (many differential ... lupus #diagnosis #sle ... erythematosus #rheumatology